5jyx: Difference between revisions
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== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/QUEFL_PYRCJ QUEFL_PYRCJ] Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA (PubMed: | [https://www.uniprot.org/uniprot/QUEFL_PYRCJ QUEFL_PYRCJ] Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA (PubMed:22032275, PubMed:28383498). Catalyzes the conversion of 7-cyano-7-deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group. Can use neither glutamine nor asparagine as amino donor in vitro, is only able to utilize free ammonium (PubMed:28383498). However, the enzyme might function in vivo with a partner that serves to generate ammonium.<ref>PMID:22032275</ref> <ref>PMID:28383498</ref> | ||
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== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
