1n2d: Difference between revisions

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[[Image:1n2d.~~gif~~|left|200px]]

[[Image:1n2d.png|left|200px]]

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~~'''~~Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin~~'''~~

===Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin===

~~==Overview==~~

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~~Mlc1p is a calmodulin~~-~~like protein from the budding yeast Saccharomyces cerevisiae, where it has been identified as a subunit of a class V myosin, Myo2p, and a binding partner of an IQGAP~~-~~like protein~~, ~~Iqg1p. Through its interactions with these two proteins~~, ~~Mlc1p plays a role in polarized growth and cytokinesis. Mlc1p has been crystallized in complexes with four different IQ target motifs from~~ the ~~neck region of Myo2p: IQ2, IQ3, IQ4 and IQ2-IQ3 (referred~~ to ~~as IQ2,3). Electron-density maps for two of~~ the ~~complexes~~ (~~Mlc1p-IQ4 and Mlc1p-IQ2,3) were obtained from multiple anomalous dispersion (MAD) experiments based~~ on ~~selenomethionine derivatives~~. ~~The other two structures (Mlc1p-IQ2 and Mlc1p-IQ3~~) ~~were determined by molecular replacement using~~ the ~~partially refined structure of Mlc1p~~-~~IQ2,3 as a search model.~~

The line below this paragraph, {{ABSTRACT_PUBMED_12351846}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 12351846 is the PubMed ID number.

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==About this Structure==

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[[Category: Myosin light chain]]

[[Category: Protein-peptide complex]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 02~~:00:16 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:11:27 2008''

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-[[Image:1n2d.gif|left|200px]]
+{{Seed}}
+[[Image:1n2d.png|left|200px]]
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 {{STRUCTURE_1n2d|  PDB=1n2d  |  SCENE=  }}
-'''Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin'''
+===Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin===
-==Overview==
+<!--
-Mlc1p is a calmodulin-like protein from the budding yeast Saccharomyces cerevisiae, where it has been identified as a subunit of a class V myosin, Myo2p, and a binding partner of an IQGAP-like protein, Iqg1p. Through its interactions with these two proteins, Mlc1p plays a role in polarized growth and cytokinesis. Mlc1p has been crystallized in complexes with four different IQ target motifs from the neck region of Myo2p: IQ2, IQ3, IQ4 and IQ2-IQ3 (referred to as IQ2,3). Electron-density maps for two of the complexes (Mlc1p-IQ4 and Mlc1p-IQ2,3) were obtained from multiple anomalous dispersion (MAD) experiments based on selenomethionine derivatives. The other two structures (Mlc1p-IQ2 and Mlc1p-IQ3) were determined by molecular replacement using the partially refined structure of Mlc1p-IQ2,3 as a search model.
+The line below this paragraph, {{ABSTRACT_PUBMED_12351846}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 12351846 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_12351846}}
 ==About this Structure==
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 [[Category: Myosin light chain]]
 [[Category: Protein-peptide complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 02:00:16 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:11:27 2008''