1na3: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
Line 1: Line 1:
[[Image:1na3.jpg|left|200px]]
{{Seed}}
[[Image:1na3.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1na3|  PDB=1na3  |  SCENE=  }}  
{{STRUCTURE_1na3|  PDB=1na3  |  SCENE=  }}  


'''Design of Stable alpha-Helical Arrays from an Idealized TPR Motif'''
===Design of Stable alpha-Helical Arrays from an Idealized TPR Motif===




==Overview==
<!--
The tetratricopeptide repeat (TPR) is a 34-amino acid alpha-helical motif that occurs in over 300 different proteins. In the different proteins, three to sixteen or more TPR motifs occur in tandem arrays and function to mediate protein-protein interactions. The binding specificity of each TPR protein is different, although the underlying structural motif is the same. Here we describe a statistical approach to the design of an idealized TPR motif. We present the high-resolution X-ray crystal structures (to 1.55 and 1.6 A) of designed TPR proteins and describe their solution properties and stability. A detailed analysis of these structures provides an understanding of the TPR motif, how it is repeated to give helical arrays with different superhelical twists, and how a very stable framework may be constructed for future functional designs.
The line below this paragraph, {{ABSTRACT_PUBMED_12737816}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12737816 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12737816}}


==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Design]]
[[Category: Design]]
[[Category: Tpr]]
[[Category: Tpr]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 02:16:55 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:21:30 2008''

Revision as of 17:21, 27 July 2008

File:1na3.png

Template:STRUCTURE 1na3

Design of Stable alpha-Helical Arrays from an Idealized TPR Motif

Template:ABSTRACT PUBMED 12737816

About this Structure

Full crystallographic information is available from OCA.

Reference

Design of stable alpha-helical arrays from an idealized TPR motif., Main ER, Xiong Y, Cocco MJ, D'Andrea L, Regan L, Structure. 2003 May;11(5):497-508. PMID:12737816

Page seeded by OCA on Sun Jul 27 20:21:30 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1na3&oldid=665257"