1nch: Difference between revisions

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[[Image:1nch.gif|left|200px]]
{{Seed}}
[[Image:1nch.png|left|200px]]


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{{STRUCTURE_1nch|  PDB=1nch  |  SCENE=  }}  
{{STRUCTURE_1nch|  PDB=1nch  |  SCENE=  }}  


'''STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS'''
===STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS===




==Overview==
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Crystal structures of the amino-terminal domain of N-cadherin provide a picture at the atomic level of a specific adhesive contact between cells. A repeated set of dimer interfaces is common to the structure in three lattices. These interactions combine to form a linear zipper of molecules that mirrors the linear structure of the intracellular filaments with which cadherins associate. This cell-adhesion zipper may provide a mechanism to marshal individual molecular adhesive interactions into strong bonds between cells.
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{{ABSTRACT_PUBMED_7885471}}


==About this Structure==
==About this Structure==
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[[Category: Thompson, A.]]
[[Category: Thompson, A.]]
[[Category: Cadherin]]
[[Category: Cadherin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 02:22:08 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:37:35 2008''

Revision as of 15:37, 27 July 2008

File:1nch.png

Template:STRUCTURE 1nch

STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS

Template:ABSTRACT PUBMED 7885471

About this Structure

1NCH is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:7885471

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