6noj: Difference between revisions

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<table><tr><td colspan='2'>[[6noj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NOJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NOJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[6noj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NOJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NOJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33&#8491;</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KW7:methyl+3-amino-4-(2-fluorophenyl)-1H-pyrrole-2-carboxylate'>KW7</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KW7:methyl+3-azanyl-4-(2-fluorophenyl)-1~{H}-pyrrole-2-carboxylate'>KW7</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6noj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6noj OCA], [https://pdbe.org/6noj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6noj RCSB], [https://www.ebi.ac.uk/pdbsum/6noj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6noj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6noj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6noj OCA], [https://pdbe.org/6noj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6noj RCSB], [https://www.ebi.ac.uk/pdbsum/6noj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6noj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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