1ntn: Difference between revisions

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[[Image:1ntn.gif|left|200px]]
{{Seed}}
[[Image:1ntn.png|left|200px]]


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{{STRUCTURE_1ntn|  PDB=1ntn  |  SCENE=  }}  
{{STRUCTURE_1ntn|  PDB=1ntn  |  SCENE=  }}  


'''THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION'''
===THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION===




==Overview==
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Neurotoxin-1 from Naja naja oxiana venom (NTX-1) has been crystallized by vapor diffusion in sitting drops. The crystals have cell dimensions of a = 25.2 A, b = 75.6 A, c = 35.9 A, and are in space group P2(1)2(1)2(1). Three-dimensional data to 1.9 A have been recorded by a Syntex P2(1) automatic diffractometer. The atomic structure of the toxin has been determined by molecular replacement using the alpha-cobratoxin (alpha-CTX) as the search model. The position of 534 non-hydrogen protein atoms have been determined. The model contains 65 water molecules. Refinement has led to an R-factor of 19.3% at 1.9 A resolution. The secondary and tertiary structures of NTX-1 have been analyzed and a comparison with structure of the alpha-CTX has been made.
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{{ABSTRACT_PUBMED_8458425}}


==About this Structure==
==About this Structure==
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[[Category: Wilson, K.]]
[[Category: Wilson, K.]]
[[Category: Postsynaptic neurotoxin]]
[[Category: Postsynaptic neurotoxin]]
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