3bwp: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwp OCA], [https://pdbe.org/3bwp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bwp RCSB], [https://www.ebi.ac.uk/pdbsum/3bwp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bwp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwp OCA], [https://pdbe.org/3bwp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bwp RCSB], [https://www.ebi.ac.uk/pdbsum/3bwp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bwp ProSAT]</span></td></tr>
</table>
</table>
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== Publication Abstract from PubMed ==
Group II introns are self-splicing ribozymes that catalyze their own excision from precursor transcripts and insertion into new genetic locations. Here we report the crystal structure of an intact, self-spliced group II intron from Oceanobacillus iheyensis at 3.1 angstrom resolution. An extensive network of tertiary interactions facilitates the ordered packing of intron subdomains around a ribozyme core that includes catalytic domain V. The bulge of domain V adopts an unusual helical structure that is located adjacent to a major groove triple helix (catalytic triplex). The bulge and catalytic triplex jointly coordinate two divalent metal ions in a configuration that is consistent with a two-metal ion mechanism for catalysis. Structural and functional analogies support the hypothesis that group II introns and the spliceosome share a common ancestor.
Crystal structure of a self-spliced group II intron.,Toor N, Keating KS, Taylor SD, Pyle AM Science. 2008 Apr 4;320(5872):77-82. PMID:18388288<ref>PMID:18388288</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 3bwp" style="background-color:#fffaf0;"></div>
== References ==
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