8odp: Difference between revisions
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==Structure of human RTCB with GMPCPP in complex with Archease== | |||
<StructureSection load='8odp' size='340' side='right'caption='[[8odp]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8odp]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ODP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ODP FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G2P:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>G2P</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8odp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8odp OCA], [https://pdbe.org/8odp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8odp RCSB], [https://www.ebi.ac.uk/pdbsum/8odp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8odp ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RTCB_HUMAN RTCB_HUMAN] Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.[HAMAP-Rule:MF_03144]<ref>PMID:21311021</ref> <ref>PMID:24870230</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Gerber JL]] | |||
[[Category: Kopp J]] | |||
[[Category: Peschek J]] | |||
Latest revision as of 10:09, 27 March 2024
Structure of human RTCB with GMPCPP in complex with Archease
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