6l4l: Difference between revisions

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<StructureSection load='6l4l' size='340' side='right'caption='[[6l4l]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='6l4l' size='340' side='right'caption='[[6l4l]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6l4l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L4L FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L4L FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l4l OCA], [https://pdbe.org/6l4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l4l RCSB], [https://www.ebi.ac.uk/pdbsum/6l4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l4l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l4l OCA], [https://pdbe.org/6l4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l4l RCSB], [https://www.ebi.ac.uk/pdbsum/6l4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l4l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CNTK_STAAM CNTK_STAAM] Catalyzes the reversible interconversion of the L- and D-stereoisomers of histidine. Functions in the biosynthesis of the metallophore staphylopine, which is involved in the acquisition of nickel, cobalt, zinc, copper, and iron, and thus enables bacterial growth inside the host, where metal access is limited. Therefore, this enzyme probably contributes to staphylococcal virulence. Appears to be specific for histidine, as it cannot use L-alanine and L-methionine as substrate.<ref>PMID:27230378</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Ju Y]]
[[Category: Ju Y]]
[[Category: Luo S]]
[[Category: Luo S]]
[[Category: Zhou H]]
[[Category: Zhou H]]

Latest revision as of 05:23, 21 November 2024

Crystal structure of S. aureus CntK in inactive state

6l4l, resolution 2.00Å

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