8qun: Difference between revisions

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'''Unreleased structure'''


The entry 8qun is ON HOLD  until Paper Publication
==human carbonic anhydrase I in complex with 2-((5-cyano-4-hydroxy-6-(p-tolyl)pyrimidin-2-yl)thio)-N-(4-sulfamoylphenyl)acetamide==
 
<StructureSection load='8qun' size='340' side='right'caption='[[8qun]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
Authors: Angeli, A., Ferraroni, M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8qun]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QUN FirstGlance]. <br>
Description: human carbonic anhydrase I in complex with 2-((5-cyano-4-hydroxy-6-(p-tolyl)pyrimidin-2-yl)thio)-N-(4-sulfamoylphenyl)acetamide
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.606&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=WZH:2-[5-cyano-4-(4-methylphenyl)-6-oxidanyl-pyrimidin-2-yl]sulfanyl-~{N}-(4-sulfamoylphenyl)ethanamide'>WZH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Ferraroni, M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qun OCA], [https://pdbe.org/8qun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qun RCSB], [https://www.ebi.ac.uk/pdbsum/8qun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qun ProSAT]</span></td></tr>
[[Category: Angeli, A]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAH1_HUMAN CAH1_HUMAN] Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.<ref>PMID:10550681</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Angeli A]]
[[Category: Ferraroni M]]

Latest revision as of 07:09, 23 October 2024

human carbonic anhydrase I in complex with 2-((5-cyano-4-hydroxy-6-(p-tolyl)pyrimidin-2-yl)thio)-N-(4-sulfamoylphenyl)acetamide

8qun, resolution 1.61Å

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