1pa4: Difference between revisions

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[[Image:1pa4.gif|left|200px]]
{{Seed}}
[[Image:1pa4.png|left|200px]]


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{{STRUCTURE_1pa4|  PDB=1pa4  |  SCENE=  }}  
{{STRUCTURE_1pa4|  PDB=1pa4  |  SCENE=  }}  


'''Solution structure of a putative ribosome-binding factor from Mycoplasma pneumoniae (MPN156)'''
===Solution structure of a putative ribosome-binding factor from Mycoplasma pneumoniae (MPN156)===




==Overview==
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The solution structure of MPN156, a ribosome-binding factor A (RBFA) protein family member from Mycoplasma pneumoniae, is presented. The structure, solved by nuclear magnetic resonance, has a type II KH fold typical of RNA binding proteins. Despite only approximately 20% sequence identity between MPN156 and another family member from Escherichia coli, the two proteins have high structural similarity. The comparison demonstrates that many of the conserved residues correspond to conserved elements in the structures. Compared to a structure based alignment, standard alignment methods based on sequence alone mispair a majority of amino acids in the two proteins. Implications of these discrepancies for sequence based structural modeling are discussed.
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{{ABSTRACT_PUBMED_15185964}}


==About this Structure==
==About this Structure==
1PA4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PA4 OCA].  
1PA4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PA4 OCA].  


==Reference==
==Reference==
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[[Category: Ribosome-binding factor]]
[[Category: Ribosome-binding factor]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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