8v89: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8v89 is ~~ON HOLD until 2025~~-12-05

==Alpha7-nicotinic acetylcholine receptor time resolved resting state==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8v89]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8V89 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8V89 FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.53Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9Z9:(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en'>9Z9</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene>, <scene name='pdbligand=R16:HEXADECANE'>R16</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8v89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8v89 OCA], [https://pdbe.org/8v89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8v89 RCSB], [https://www.ebi.ac.uk/pdbsum/8v89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8v89 ProSAT]</td></tr>

</table>

== Disease ==

[https://www.uniprot.org/uniprot/ACHA7_HUMAN ACHA7_HUMAN] 15q13.3 microdeletion syndrome.

== Function ==

[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/ACHA7_HUMAN ACHA7_HUMAN] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Burke SM]]

[[Category: Hibbs RE]]

[[Category: Noviello CM]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8v89 is ON HOLD  until 2025-12-05
+==Alpha7-nicotinic acetylcholine receptor time resolved resting state==
+<StructureSection load='8v89' size='340' side='right'caption='[[8v89]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8v89]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8V89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8V89 FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.53&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9Z9:(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en'>9Z9</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene>, <scene name='pdbligand=R16:HEXADECANE'>R16</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8v89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8v89 OCA], [https://pdbe.org/8v89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8v89 RCSB], [https://www.ebi.ac.uk/pdbsum/8v89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8v89 ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/ACHA7_HUMAN ACHA7_HUMAN] 15q13.3 microdeletion syndrome.
+== Function ==
+[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/ACHA7_HUMAN ACHA7_HUMAN] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Burke SM]]
+[[Category: Hibbs RE]]
+[[Category: Noviello CM]]