1rbp: Difference between revisions

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[[Image:1rbp.gif|left|200px]]<br />

[[Image:1rbp.gif|left|200px]]<br /><applet load="1rbp" size="350" color="white" frame="true" align="right" spinBox="true"

<applet load="1rbp" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

caption="1rbp, resolution 2.0Å" />

'''CRYSTALLOGRAPHIC REFINEMENT OF HUMAN SERUM RETINOL BINDING PROTEIN AT 2 ANGSTROMS RESOLUTION'''<br />

==Overview==

Human serum retinol binding protein (RBP) in complex with retinol has been, crystallographically refined to an R-factor of 18.1% with 2A resolution, data. The protein topology results in an anti-parallel beta-barrel that, encapsulates the retinol ligand. A detailed description of the protein and, the binding site is provided. Our structural work has helped to define a, family of proteins, many of which are carrier proteins for smaller ligand, molecules. We describe the structural basis for the conservation of, sequence within the family.

Human serum retinol binding protein (RBP) in complex with retinol has been crystallographically refined to an R-factor of 18.1% with 2A resolution data. The protein topology results in an anti-parallel beta-barrel that encapsulates the retinol ligand. A detailed description of the protein and the binding site is provided. Our structural work has helped to define a family of proteins, many of which are carrier proteins for smaller ligand molecules. We describe the structural basis for the conservation of sequence within the family.

==Disease==

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==About this Structure==

1RBP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with RTL as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1RBP OCA].

1RBP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=RTL:'>RTL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RBP OCA].

==Reference==

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[[Category: Homo sapiens]]

[[Category: Single protein]]

[[Category: Cowan, S.W.]]

[[Category: Cowan, S W.]]

[[Category: Jones, T.A.]]

[[Category: Jones, T A.]]

[[Category: Newcomer, M.E.]]

[[Category: Newcomer, M E.]]

[[Category: RTL]]

[[Category: retinol transport]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Mon Nov 12 19~~:01:~~48 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:49:10 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1rbp.gif|left|200px]]<br />
+[[Image:1rbp.gif|left|200px]]<br /><applet load="1rbp" size="350" color="white" frame="true" align="right" spinBox="true"
-<applet load="1rbp" size="450" color="white" frame="true" align="right" spinBox="true"
 caption="1rbp, resolution 2.0&Aring;" />
 '''CRYSTALLOGRAPHIC REFINEMENT OF HUMAN SERUM RETINOL BINDING PROTEIN AT 2 ANGSTROMS RESOLUTION'''<br />
 ==Overview==
-Human serum retinol binding protein (RBP) in complex with retinol has been, crystallographically refined to an R-factor of 18.1% with 2A resolution, data. The protein topology results in an anti-parallel beta-barrel that, encapsulates the retinol ligand. A detailed description of the protein and, the binding site is provided. Our structural work has helped to define a, family of proteins, many of which are carrier proteins for smaller ligand, molecules. We describe the structural basis for the conservation of, sequence within the family.
+Human serum retinol binding protein (RBP) in complex with retinol has been crystallographically refined to an R-factor of 18.1% with 2A resolution data. The protein topology results in an anti-parallel beta-barrel that encapsulates the retinol ligand. A detailed description of the protein and the binding site is provided. Our structural work has helped to define a family of proteins, many of which are carrier proteins for smaller ligand molecules. We describe the structural basis for the conservation of sequence within the family.
 ==Disease==
@@ Line 11: / Line 10: @@
 ==About this Structure==
-RBP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with RTL as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1RBP OCA].
+RBP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=RTL:'>RTL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RBP OCA].
 ==Reference==
@@ Line 17: / Line 16: @@
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
-[[Category: Cowan, S.W.]]
+[[Category: Cowan, S W.]]
-[[Category: Jones, T.A.]]
+[[Category: Jones, T A.]]
-[[Category: Newcomer, M.E.]]
+[[Category: Newcomer, M E.]]
 [[Category: RTL]]
 [[Category: retinol transport]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 19:01:48 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:49:10 2008''