8x63: Difference between revisions
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<table><tr><td colspan='2'>[[8x63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8X63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8X63 FirstGlance]. <br> | <table><tr><td colspan='2'>[[8x63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8X63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8X63 FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Y5E: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Y5E:~{N}-[(4-methoxyphenyl)methyl]-~{N},~{N}-dimethyl-~{N}-pyridin-2-yl-ethane-1,2-diamine'>Y5E</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8x63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8x63 OCA], [https://pdbe.org/8x63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8x63 RCSB], [https://www.ebi.ac.uk/pdbsum/8x63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8x63 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8x63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8x63 OCA], [https://pdbe.org/8x63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8x63 RCSB], [https://www.ebi.ac.uk/pdbsum/8x63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8x63 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/HRH1_HUMAN HRH1_HUMAN] In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Latest revision as of 07:30, 27 November 2024
CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with mepyramine
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