7av8: Difference between revisions

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<StructureSection load='7av8' size='340' side='right'caption='[[7av8]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
<StructureSection load='7av8' size='340' side='right'caption='[[7av8]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7av8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AV8 FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AV8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7av8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7av8 OCA], [https://pdbe.org/7av8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7av8 RCSB], [https://www.ebi.ac.uk/pdbsum/7av8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7av8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7av8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7av8 OCA], [https://pdbe.org/7av8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7av8 RCSB], [https://www.ebi.ac.uk/pdbsum/7av8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7av8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PHIP_HUMAN PHIP_HUMAN] Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:12242307</ref> <ref>PMID:21834987</ref>


==See Also==
==See Also==
*[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]]
*[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Arrowsmith CH]]

Latest revision as of 05:47, 7 August 2024

Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group P21212

7av8, resolution 1.63Å

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