8als: Difference between revisions

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==The apo-crystal structure ~~of a variant form~~ of the 28-kDa Schistosoma ~~haematobium~~ glutathione transferase==

==The apo-crystal structure of the 28-kDa Schistosoma bovis glutathione transferase==

== Structural highlights ==

<table><tr><td colspan='2'>[[8als]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Schistosoma_haematobium~~ Schistosoma ~~haematobium~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ALS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ALS FirstGlance]. <br>

<table><tr><td colspan='2'>[[8als]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_bovis Schistosoma bovis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ALS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ALS FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>

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</table>

== Function ==

[https://www.uniprot.org/uniprot/~~GST28_SCHHA GST28_SCHHA~~] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.~~<ref>PMID:12939136</ref>~~ GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.~~<ref>PMID:12939136</ref>~~

[https://www.uniprot.org/uniprot/GST28_SCHBO GST28_SCHBO] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.

==See Also==

*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]

~~== References ==~~

~~<references/>~~

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Schistosoma ~~haematobium~~]]

[[Category: Schistosoma bovis]]

[[Category: Achilonu IA]]

[[Category: Makumbe HH]]

[[Category: Pandian R]]

[[Category: Sayed Y]]

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@@ Line 1: / Line 1: @@
-==The apo-crystal structure of a variant form of the 28-kDa Schistosoma haematobium glutathione transferase==
+==The apo-crystal structure of the 28-kDa Schistosoma bovis glutathione transferase==
 <StructureSection load='8als' size='340' side='right'caption='[[8als]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[8als]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_haematobium Schistosoma haematobium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ALS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ALS FirstGlance]. <br>
+<table><tr><td colspan='2'>[[8als]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_bovis Schistosoma bovis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ALS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ALS FirstGlance]. <br>
 </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
 <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
@@ Line 9: / Line 9: @@
 </table>
 == Function ==
-[https://www.uniprot.org/uniprot/GST28_SCHHA GST28_SCHHA] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:12939136</ref>   GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.<ref>PMID:12939136</ref>
+[https://www.uniprot.org/uniprot/GST28_SCHBO GST28_SCHBO] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.
 ==See Also==
 *[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
-== References ==
-<references/>
 __TOC__
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Schistosoma haematobium]]
+[[Category: Schistosoma bovis]]
 [[Category: Achilonu IA]]
 [[Category: Makumbe HH]]
 [[Category: Pandian R]]
 [[Category: Sayed Y]]