8aav: Difference between revisions

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'''Unreleased structure'''


The entry 8aav is ON HOLD
==Human heavy chain ferritin with introduced Cys residues modified with C10 ligand==
 
<StructureSection load='8aav' size='340' side='right'caption='[[8aav]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
Authors: Boehler, H., Beck, T.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8aav]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AAV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AAV FirstGlance]. <br>
Description: Human heavy chain ferritin with introduced Cys residues modified with C10 ligand
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=O3K:2-bromanyl-N-decyl-ethanamide'>O3K</scene></td></tr>
[[Category: Beck, T]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8aav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8aav OCA], [https://pdbe.org/8aav PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8aav RCSB], [https://www.ebi.ac.uk/pdbsum/8aav PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8aav ProSAT]</span></td></tr>
[[Category: Boehler, H]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Beck T]]
[[Category: Boehler H]]