8xzf: Difference between revisions
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==Cryo-EM structure of the WN561-bound human APLNR-Gi complex== | |||
<StructureSection load='8xzf' size='340' side='right'caption='[[8xzf]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8xzf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XZF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MED:D-METHIONINE'>MED</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xzf OCA], [https://pdbe.org/8xzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xzf RCSB], [https://www.ebi.ac.uk/pdbsum/8xzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xzf ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/APJ_HUMAN APJ_HUMAN] Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Ji S]] | |||
[[Category: Wang W]] | |||
[[Category: Zhang Y]] | |||
Revision as of 08:22, 20 March 2024
Cryo-EM structure of the WN561-bound human APLNR-Gi complex
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