1q6k: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:1q6k.jpg|left|200px]]
{{Seed}}
[[Image:1q6k.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1q6k|  PDB=1q6k  |  SCENE=  }}  
{{STRUCTURE_1q6k|  PDB=1q6k  |  SCENE=  }}  


'''Cathepsin K complexed with t-butyl(1S)-1-cyclohexyl-2-oxoethylcarbamate'''
===Cathepsin K complexed with t-butyl(1S)-1-cyclohexyl-2-oxoethylcarbamate===




==Overview==
<!--
The synthesis and biological activity of a series of aldehyde inhibitors of cathepsin K are reported. Exploration of the properties of the S(1) subsite with a series of alpha-amino aldehyde derivatives substituted at the P(1) position afforded compounds with cathepsin K IC(50)s between 52 microM and 15 nM.
The line below this paragraph, {{ABSTRACT_PUBMED_14684342}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 14684342 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_14684342}}


==About this Structure==
==About this Structure==
Line 35: Line 39:
[[Category: Cathepsin k]]
[[Category: Cathepsin k]]
[[Category: Catk]]
[[Category: Catk]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 05:55:35 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:48:26 2008''

Revision as of 10:48, 28 July 2008

File:1q6k.png

Template:STRUCTURE 1q6k

Cathepsin K complexed with t-butyl(1S)-1-cyclohexyl-2-oxoethylcarbamate

Template:ABSTRACT PUBMED 14684342

About this Structure

1Q6K is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Exploration of the P1 SAR of aldehyde cathepsin K inhibitors., Catalano JG, Deaton DN, Furfine ES, Hassell AM, McFadyen RB, Miller AB, Miller LR, Shewchuk LM, Willard DH Jr, Wright LL, Bioorg Med Chem Lett. 2004 Jan 5;14(1):275-8. PMID:14684342

Page seeded by OCA on Mon Jul 28 13:48:26 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA