1qf5: Difference between revisions

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[[Image:1qf5.jpg|left|200px]]
{{Seed}}
[[Image:1qf5.png|left|200px]]


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{{STRUCTURE_1qf5|  PDB=1qf5  |  SCENE=  }}  
{{STRUCTURE_1qf5|  PDB=1qf5  |  SCENE=  }}  


'''DESIGN, SYNTHESIS, AND X-RAY CRYSTAL STRUCTURE OF AN ENZYME BOUND BISUBSTRATE HYBRID INHIBITOR OF ADENYLOSUCCINATE SYNTHETASE'''
===DESIGN, SYNTHESIS, AND X-RAY CRYSTAL STRUCTURE OF AN ENZYME BOUND BISUBSTRATE HYBRID INHIBITOR OF ADENYLOSUCCINATE SYNTHETASE===




==Overview==
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Two relatively weak herbicides, hydantocidin phosphate and hadacidin were linked by a C(3) chain to afford a potent inhibitor (the 2S hybrid is shown) of the enzyme adenylosuccinate synthetase. The crystal structures of the bisubstrate-enzyme complexes were determined.
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{{ABSTRACT_PUBMED_10556888}}


==About this Structure==
==About this Structure==
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[[Category: Purine biosynthesis]]
[[Category: Purine biosynthesis]]
[[Category: Synthetase]]
[[Category: Synthetase]]
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