1qh2: Difference between revisions

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[[Image:1qh2.~~jpg~~|left|200px]]

[[Image:1qh2.png|left|200px]]

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~~'''~~CHYMOTRYPSIN INHIBITOR (C2) FROM NICOTIANA ALATA~~'''~~

===CHYMOTRYPSIN INHIBITOR (C2) FROM NICOTIANA ALATA===

~~==Overview==~~

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~~Female reproductive tissues of~~ the ~~ornamental tobacco amass high levels of serine proteinase inhibitors~~ (~~PIs) for protection against pests and pathogens~~. ~~These PIs are produced from a precursor protein composed of six repeats each with a protease reactive site~~. Here we show that proteolytic processing of the precursor generates five single-chain PIs and a remarkable two-chain inhibitor formed by disulfide-bond linkage of N- and C-terminal peptide fragments. Surprisingly, ~~PI precursors adopt this circular structure regardless of~~ the number ~~of inhibitor domains, suggesting this bracelet~~-~~like conformation is characteristic of the widespread potato inhibitor II (Pot II) protein family.~~

The line below this paragraph, {{ABSTRACT_PUBMED_10360353}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 10360353 is the PubMed ID number.

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==About this Structure==

1QH2 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Nicotiana_alata Nicotiana alata]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QH2 OCA].

1QH2 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Nicotiana_alata Nicotiana alata]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QH2 OCA].

==Reference==

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[[Category: Potato ii trypsin inhibitor]]

[[Category: Serine proteinase inhibitor]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 06~~:15:48 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:07:02 2008''

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-[[Image:1qh2.jpg|left|200px]]
+{{Seed}}
+[[Image:1qh2.png|left|200px]]
 <!--
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 {{STRUCTURE_1qh2|  PDB=1qh2  |  SCENE=  }}
-'''CHYMOTRYPSIN INHIBITOR (C2) FROM NICOTIANA ALATA'''
+===CHYMOTRYPSIN INHIBITOR (C2) FROM NICOTIANA ALATA===
-==Overview==
+<!--
-Female reproductive tissues of the ornamental tobacco amass high levels of serine proteinase inhibitors (PIs) for protection against pests and pathogens. These PIs are produced from a precursor protein composed of six repeats each with a protease reactive site. Here we show that proteolytic processing of the precursor generates five single-chain PIs and a remarkable two-chain inhibitor formed by disulfide-bond linkage of N- and C-terminal peptide fragments. Surprisingly, PI precursors adopt this circular structure regardless of the number of inhibitor domains, suggesting this bracelet-like conformation is characteristic of the widespread potato inhibitor II (Pot II) protein family.
+The line below this paragraph, {{ABSTRACT_PUBMED_10360353}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 10360353 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_10360353}}
 ==About this Structure==
-QH2 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Nicotiana_alata Nicotiana alata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QH2 OCA].
+QH2 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Nicotiana_alata Nicotiana alata]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QH2 OCA].
 ==Reference==
@@ Line 29: / Line 33: @@
 [[Category: Potato ii trypsin inhibitor]]
 [[Category: Serine proteinase inhibitor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 06:15:48 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:07:02 2008''