1srs: Difference between revisions

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New page: left|200px<br /> <applet load="1srs" size="450" color="white" frame="true" align="right" spinBox="true" caption="1srs, resolution 3.200Å" /> '''SERUM RESPONSE FAC...
 
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[[Image:1srs.gif|left|200px]]<br />
[[Image:1srs.gif|left|200px]]<br /><applet load="1srs" size="350" color="white" frame="true" align="right" spinBox="true"  
<applet load="1srs" size="450" color="white" frame="true" align="right" spinBox="true"  
caption="1srs, resolution 3.200&Aring;" />
caption="1srs, resolution 3.200&Aring;" />
'''SERUM RESPONSE FACTOR (SRF) CORE COMPLEXED WITH SPECIFIC SRE DNA'''<br />
'''SERUM RESPONSE FACTOR (SRF) CORE COMPLEXED WITH SPECIFIC SRE DNA'''<br />


==Overview==
==Overview==
The human serum response factor is a transcription factor belonging to the, MADS domain protein family with members characterized from the plant and, animal kingdoms. The X-ray crystal structure of the serum response factor, core in a specific-recognition DNA complex shows that the functions of DNA, binding, dimerization and accessory-factor interaction are compactly, integrated into a novel protein unit. The intrinsic and induced, conformation of the serum response element DNA is the principal DNA, feature recognized in the specific complex.
The human serum response factor is a transcription factor belonging to the MADS domain protein family with members characterized from the plant and animal kingdoms. The X-ray crystal structure of the serum response factor core in a specific-recognition DNA complex shows that the functions of DNA binding, dimerization and accessory-factor interaction are compactly integrated into a novel protein unit. The intrinsic and induced conformation of the serum response element DNA is the principal DNA feature recognized in the specific complex.


==Disease==
==Disease==
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==About this Structure==
==About this Structure==
1SRS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1SRS OCA].  
1SRS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SRS OCA].  


==Reference==
==Reference==
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[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Pellegrini, L.]]
[[Category: Pellegrini, L.]]
[[Category: Richmond, T.J.]]
[[Category: Richmond, T J.]]
[[Category: Tan, S.]]
[[Category: Tan, S.]]
[[Category: complex (dna binding protein/dna)]]
[[Category: complex (dna binding protein/dna)]]
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[[Category: transcription regulation]]
[[Category: transcription regulation]]


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