1srs: Difference between revisions
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New page: left|200px<br /> <applet load="1srs" size="450" color="white" frame="true" align="right" spinBox="true" caption="1srs, resolution 3.200Å" /> '''SERUM RESPONSE FAC... |
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[[Image:1srs.gif|left|200px]]<br /> | [[Image:1srs.gif|left|200px]]<br /><applet load="1srs" size="350" color="white" frame="true" align="right" spinBox="true" | ||
<applet load="1srs" size=" | |||
caption="1srs, resolution 3.200Å" /> | caption="1srs, resolution 3.200Å" /> | ||
'''SERUM RESPONSE FACTOR (SRF) CORE COMPLEXED WITH SPECIFIC SRE DNA'''<br /> | '''SERUM RESPONSE FACTOR (SRF) CORE COMPLEXED WITH SPECIFIC SRE DNA'''<br /> | ||
==Overview== | ==Overview== | ||
The human serum response factor is a transcription factor belonging to the | The human serum response factor is a transcription factor belonging to the MADS domain protein family with members characterized from the plant and animal kingdoms. The X-ray crystal structure of the serum response factor core in a specific-recognition DNA complex shows that the functions of DNA binding, dimerization and accessory-factor interaction are compactly integrated into a novel protein unit. The intrinsic and induced conformation of the serum response element DNA is the principal DNA feature recognized in the specific complex. | ||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
1SRS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http:// | 1SRS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SRS OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Pellegrini, L.]] | [[Category: Pellegrini, L.]] | ||
[[Category: Richmond, T | [[Category: Richmond, T J.]] | ||
[[Category: Tan, S.]] | [[Category: Tan, S.]] | ||
[[Category: complex (dna binding protein/dna)]] | [[Category: complex (dna binding protein/dna)]] | ||
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[[Category: transcription regulation]] | [[Category: transcription regulation]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:04:34 2008'' | ||