1qo8: Difference between revisions

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[[Image:1qo8.gif|left|200px]]
{{Seed}}
[[Image:1qo8.png|left|200px]]


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{{STRUCTURE_1qo8|  PDB=1qo8  |  SCENE=  }}  
{{STRUCTURE_1qo8|  PDB=1qo8  |  SCENE=  }}  


'''THE STRUCTURE OF THE OPEN CONFORMATION OF A FLAVOCYTOCHROME C3 FUMARATE REDUCTASE'''
===THE STRUCTURE OF THE OPEN CONFORMATION OF A FLAVOCYTOCHROME C3 FUMARATE REDUCTASE===




==Overview==
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Fumarate reductases and succinate dehydrogenases play central roles in the metabolism of eukaryotic and prokaryotic cells. A recent medium resolution structure of the Escherichia coli fumarate reductase (Frd) has revealed the overall organization of the membrane-bound complex. Here we present the first high resolution X-ray crystal structure of a water-soluble bacterial fumarate reductase in an open conformation. This structure reveals a mobile domain that modulates substrate access to the active site and provides new insights into the mechanism of this widespread and important family of FAD-containing respiratory proteins.
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{{ABSTRACT_PUBMED_10581549}}


==About this Structure==
==About this Structure==
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[[Category: Richardson, D J.]]
[[Category: Richardson, D J.]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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