1qou: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
Line 1: Line 1:
[[Image:1qou.gif|left|200px]]
{{Seed}}
[[Image:1qou.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1qou|  PDB=1qou  |  SCENE=  }}  
{{STRUCTURE_1qou|  PDB=1qou  |  SCENE=  }}  


'''CEN (CENTRORADIALIS) PROTEIN FROM ANTIRRHINUM'''
===CEN (CENTRORADIALIS) PROTEIN FROM ANTIRRHINUM===




==Overview==
<!--
Expression of the plant protein centroradialis (CEN) leads to a morphological switch between shoot growth and the development of flower structures (inflorescence). We have determined the crystal structure of Antirrhinum CEN to 1.9 A resolution. This structure confirms the CEN proteins as a subset of the family of phosphatidylethanolamine-binding proteins (PEBP), as predicted from sequence homology. Mammalian forms of PEBP have been found to act as inhibitors of MAP kinase signalling, a central signalling cascade regulating cell differentiation. CEN and PEBP proteins share a similar topology dominated by a large central beta-sheet. The strong conservation of a binding pocket at one end of this sheet which is capable of binding phosphoryl ligands, suggests the biological effects of CEN, like PEBP, arise from the ability of this region to form complexes with phosphorylated ligands, hence interfering with kinases and their effectors.
The line below this paragraph, {{ABSTRACT_PUBMED_10764580}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 10764580 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_10764580}}


==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Member of the phosphatidylethanolamine binding protein family]]
[[Category: Member of the phosphatidylethanolamine binding protein family]]
[[Category: Signalling]]
[[Category: Signalling]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 06:31:47 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 12:36:46 2008''
Retrieved from "https://proteopedia.org/1qou"