1qqh: Difference between revisions

Line 1:

[[Image:1qqh.~~gif~~|left|200px]]

[[Image:1qqh.png|left|200px]]

<!--

Line 9:

Line 10:

~~'''~~2.1 A CRYSTAL STRUCTURE OF THE HUMAN PAPILLOMAVIRUS TYPE 18 E2 ACTIVATION DOMAIN~~'''~~

===2.1 A CRYSTAL STRUCTURE OF THE HUMAN PAPILLOMAVIRUS TYPE 18 E2 ACTIVATION DOMAIN===

~~==Overview==~~

<!--

The ~~papillomavirus E2 protein regulates viral transcription and DNA replication through interactions with cellular and viral proteins. The amino-terminal activation domain~~, ~~which represents a protein class whose structural themes are poorly understood~~, ~~contains key residues that mediate these functional contacts. The crystal structure of a protease-resistant core of~~ the ~~human papillomavirus type 18 E2 activation domain reveals a novel fold creating a cashew-shaped form with a glutamine-rich alpha helix packed against a beta-sheet framework~~. ~~The protein surface shows extensive overlap of determinants for replication and transcription~~. ~~The structure broadens~~ the ~~concept of activators to include proteins with potentially malleable, but certainly ordered, structures~~.

The line below this paragraph, {{ABSTRACT_PUBMED_10356398}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 10356398 is the PubMed ID number.

-->

==About this Structure==

Line 26:

Line 30:

[[Category: Amphipathic helix]]

[[Category: Cashew/kidney shape]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 06~~:35:14 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:59:42 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:1qqh.gif|left|200px]]
+{{Seed}}
+[[Image:1qqh.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_1qqh|  PDB=1qqh  |  SCENE=  }}
-'''2.1 A CRYSTAL STRUCTURE OF THE HUMAN PAPILLOMAVIRUS TYPE 18 E2 ACTIVATION DOMAIN'''
+===2.1 A CRYSTAL STRUCTURE OF THE HUMAN PAPILLOMAVIRUS TYPE 18 E2 ACTIVATION DOMAIN===
-==Overview==
+<!--
-The papillomavirus E2 protein regulates viral transcription and DNA replication through interactions with cellular and viral proteins. The amino-terminal activation domain, which represents a protein class whose structural themes are poorly understood, contains key residues that mediate these functional contacts. The crystal structure of a protease-resistant core of the human papillomavirus type 18 E2 activation domain reveals a novel fold creating a cashew-shaped form with a glutamine-rich alpha helix packed against a beta-sheet framework. The protein surface shows extensive overlap of determinants for replication and transcription. The structure broadens the concept of activators to include proteins with potentially malleable, but certainly ordered, structures.
+The line below this paragraph, {{ABSTRACT_PUBMED_10356398}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 10356398 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_10356398}}
 ==About this Structure==
@@ Line 26: / Line 30: @@
 [[Category: Amphipathic helix]]
 [[Category: Cashew/kidney shape]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 06:35:14 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:59:42 2008''