1r27: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
Line 1: Line 1:
[[Image:1r27.gif|left|200px]]
{{Seed}}
[[Image:1r27.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1r27|  PDB=1r27  |  SCENE=  }}  
{{STRUCTURE_1r27|  PDB=1r27  |  SCENE=  }}  


'''Crystal Structure of NarGH complex'''
===Crystal Structure of NarGH complex===




==Overview==
<!--
The structure of the catalytic and electron-transfer subunits (NarGH) of the integral membrane protein, respiratory nitrate reductase (Nar) has been determined to 2.0 A resolution revealing the molecular architecture of this Mo-bisMGD (molybdopterin-guanine-dinucleotide) containing enzyme which includes a previously undetected FeS cluster. Nar, together with the related enzyme formate dehydrogenase (Fdh-N), is a key enzyme in the generation of proton motive force across the membrane in Escherichia coli nitrate respiration. A comparative study revealed that Nar and Fdh-N employ different approaches for acquiring substrate, reflecting different catalytic mechanisms. Nar uses a very narrow and nonpolar substrate-conducting cavity with a nonspecific substrate binding site, whereas Fdh-N accommodates a wider, positively charged substrate-conducting cavity with a more specific substrate binding site. The Nar structure also demonstrates the first example of an Asp side chain acting as a Mo ligand providing a structural basis for the classification of Mo-bisMGD enzymes.
The line below this paragraph, {{ABSTRACT_PUBMED_14725769}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 14725769 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_14725769}}


==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: X-ray crystallography]]
[[Category: X-ray crystallography]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 06:59:05 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:35:16 2008''

Revision as of 20:35, 27 July 2008

File:1r27.png

Template:STRUCTURE 1r27

Crystal Structure of NarGH complex

Template:ABSTRACT PUBMED 14725769

About this Structure

1R27 is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Architecture of NarGH reveals a structural classification of Mo-bisMGD enzymes., Jormakka M, Richardson D, Byrne B, Iwata S, Structure. 2004 Jan;12(1):95-104. PMID:14725769

Page seeded by OCA on Sun Jul 27 23:35:16 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1r27&oldid=671497"