1rec: Difference between revisions

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[[Image:1rec.gif|left|200px]]
{{Seed}}
[[Image:1rec.png|left|200px]]


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{{STRUCTURE_1rec|  PDB=1rec  |  SCENE=  }}  
{{STRUCTURE_1rec|  PDB=1rec  |  SCENE=  }}  


'''THREE-DIMENSIONAL STRUCTURE OF RECOVERIN, A CALCIUM SENSOR IN VISION'''
===THREE-DIMENSIONAL STRUCTURE OF RECOVERIN, A CALCIUM SENSOR IN VISION===




==Overview==
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Recoverin, a recently discovered member of the EF hand superfamily, serves as a calcium sensor in vision. We report here the crystal structure of recombinant unmyristoylated recoverin at 1.9 A resolution. The four EF hands of the protein are arranged in a compact array that contrasts with the dumbbell shape of calmodulin and troponin C. A calcium ion is bound to EF hand 3, while EF hand 2 can bind samarium but not calcium in this crystal form. The other two EF hands have novel structural features that prevent or impair calcium binding. A concave hydrophobic surface formed by EF hands 1 and 2 may participate in the read out of calcium signals by recoverin and its homologs.
The line below this paragraph, {{ABSTRACT_PUBMED_8242744}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_8242744}}


==About this Structure==
==About this Structure==
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[[Category: Zozulya, S.]]
[[Category: Zozulya, S.]]
[[Category: Calcium-binding protein]]
[[Category: Calcium-binding protein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 07:23:36 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:51:54 2008''

Revision as of 20:51, 28 July 2008

File:1rec.png

Template:STRUCTURE 1rec

THREE-DIMENSIONAL STRUCTURE OF RECOVERIN, A CALCIUM SENSOR IN VISION

Template:ABSTRACT PUBMED 8242744

About this Structure

1REC is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Three-dimensional structure of recoverin, a calcium sensor in vision., Flaherty KM, Zozulya S, Stryer L, McKay DB, Cell. 1993 Nov 19;75(4):709-16. PMID:8242744

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