8y6l: Difference between revisions
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==Oryza sativa HKT1;5 salt sensitive variant== | |||
<StructureSection load='8y6l' size='340' side='right'caption='[[8y6l]], [[Resolution|resolution]] 3.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8y6l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Y6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Y6L FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8y6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8y6l OCA], [https://pdbe.org/8y6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8y6l RCSB], [https://www.ebi.ac.uk/pdbsum/8y6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8y6l ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HKT15_ORYSJ HKT15_ORYSJ] Sodium transporter that under salt stress mediates sodium exclusion in the phloem to prevent sodium transfer to young leaf blades and reproductive tissues.<ref>PMID:28488420</ref> [https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function. | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The high-affinity potassium transporters (HKTs), selectively permeable to either Na(+) alone or Na(+)/K(+), play pivotal roles in maintaining plant Na(+)/K(+) homeostasis. Although their involvement in salt tolerance is widely reported, the molecular underpinnings of Oryza sativa HKTs remain elusive. In this study, we elucidate the structures of OsHKT1;1 and OsHKT2;1, representing two distinct classes of rice HKTs. The dimeric assembled OsHKTs can be structurally divided into four domains. At the dimer interface, a half-helix or a loop in the third domain is coordinated by the C-terminal region of the opposite subunit. Additionally, we present the structures of OsHKT1;5 salt-tolerant and salt-sensitive variants, a key quantitative trait locus associated with salt tolerance. The salt-tolerant variant of OsHKT1;5 exhibits enhanced Na(+) transport capability and displays a more flexible conformation. These findings shed light on the molecular basis of rice HKTs and provide insights into their role in salt tolerance. | |||
Structural insights into the Oryza sativa cation transporters HKTs in salt tolerance.,Gao R, Jia Y, Xu X, Fu P, Zhou J, Yang G J Integr Plant Biol. 2024 Apr;66(4):700-708. doi: 10.1111/jipb.13632. Epub 2024 , Feb 26. PMID:38409933<ref>PMID:38409933</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
<div class="pdbe-citations 8y6l" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | |||
[[Category: Oryza sativa]] | |||
[[Category: Gao R]] | |||
[[Category: Yang GH]] | |||
Latest revision as of 20:00, 11 December 2024
Oryza sativa HKT1;5 salt sensitive variant
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