7g0b: Difference between revisions

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==Crystal Structure of human FABP5 in complex with 7-bromo-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1-benzazepine-4-carboxylic acid==

==Crystal Structure of human FABP5 in complex with 7-bromo-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1-benzazepine-4-carboxylic acid, i.e. SMILES [C@@H]1([C@@H](CCN(c2c1cc(cc2)Br)C)C(=O)O)c1ccccc1 with IC50=2.3 microM==

== Structural highlights ==

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g0b OCA], [https://pdbe.org/7g0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g0b RCSB], [https://www.ebi.ac.uk/pdbsum/7g0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g0b ProSAT]</span></td></tr>

</table>

~~== Function ==~~

[https://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.

__TOC__

</StructureSection>

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-==Crystal Structure of human FABP5 in complex with 7-bromo-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1-benzazepine-4-carboxylic acid==
+==Crystal Structure of human FABP5 in complex with 7-bromo-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1-benzazepine-4-carboxylic acid, i.e. SMILES [C@@H]1([C@@H](CCN(c2c1cc(cc2)Br)C)C(=O)O)c1ccccc1 with IC50=2.3 microM==
 <StructureSection load='7g0b' size='340' side='right'caption='[[7g0b]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
 == Structural highlights ==
@@ Line 8: / Line 8: @@
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g0b OCA], [https://pdbe.org/7g0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g0b RCSB], [https://www.ebi.ac.uk/pdbsum/7g0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g0b ProSAT]</span></td></tr>
 </table>
-== Function ==
-[https://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.
 __TOC__
 </StructureSection>