1tze: Difference between revisions
New page: left|200px<br /> <applet load="1tze" size="450" color="white" frame="true" align="right" spinBox="true" caption="1tze, resolution 2.1Å" /> '''SIGNAL TRANSDUCTION ... |
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[[Image:1tze. | [[Image:1tze.jpg|left|200px]]<br /><applet load="1tze" size="350" color="white" frame="true" align="right" spinBox="true" | ||
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caption="1tze, resolution 2.1Å" /> | caption="1tze, resolution 2.1Å" /> | ||
'''SIGNAL TRANSDUCTION ADAPTOR GROWTH FACTOR, GRB2 SH2 DOMAIN COMPLEXED WITH PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 (KFPPYVNC-NH2)'''<br /> | '''SIGNAL TRANSDUCTION ADAPTOR GROWTH FACTOR, GRB2 SH2 DOMAIN COMPLEXED WITH PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 (KFPPYVNC-NH2)'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
1TZE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with NH2 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | 1TZE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZE OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: signal transduction adaptor growth factor bound protein 2 (grb2) src homology 2 domain (sh2)]] | [[Category: signal transduction adaptor growth factor bound protein 2 (grb2) src homology 2 domain (sh2)]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Feb 15 16:58:57 2008'' | ||
Revision as of 14:58, 15 February 2008
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SIGNAL TRANSDUCTION ADAPTOR GROWTH FACTOR, GRB2 SH2 DOMAIN COMPLEXED WITH PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 (KFPPYVNC-NH2)
Disease
Known diseases associated with this structure: Central hypoventilation syndrome, congenital OMIM:[100790], Haddad syndrome OMIM:[100790]
About this Structure
1TZE is a Single protein structure of sequence from Homo sapiens with NH2 as ligand. Full crystallographic information is available from OCA.
Reference
Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode., Rahuel J, Gay B, Erdmann D, Strauss A, Garcia-Echeverria C, Furet P, Caravatti G, Fretz H, Schoepfer J, Grutter MG, Nat Struct Biol. 1996 Jul;3(7):586-9. PMID:8673601
Page seeded by OCA on Fri Feb 15 16:58:57 2008
