User:Mandy Bechman/Sandbox 1: Difference between revisions
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=H. sapiens Glucose-dependent Insulinotropic Polypeptide= | =H. sapiens Glucose-dependent Insulinotropic Polypeptide= | ||
<StructureSection load='7ra3' size=' | <StructureSection load='7ra3' size='400' side='right' caption='GIP Structure' scene='10/1038867/Structure_overview/3'> | ||
==Introduction== | ==Introduction== | ||
Glucose-dependent insulinotropic polypeptide ([https://pubmed.ncbi.nlm.nih.gov/35065096/ GIP]) <ref name="Mayendraraj"/> is a gastric inhibitory polypeptide. It is categorized as a incretin, which is a gut-based hormone that is secreted upon the ingestion of food. It is found in K cells in the upper small intestines of humans. | Glucose-dependent insulinotropic polypeptide ([https://pubmed.ncbi.nlm.nih.gov/35065096/ GIP]) <ref name="Mayendraraj"/> is a gastric inhibitory polypeptide. It is categorized as a incretin, which is a gut-based hormone that is secreted upon the ingestion of food. It is found in K cells in the upper small intestines of humans. | ||
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== Function == | == Function == | ||
[[Image:GIPmech.jpg|350 px|left|thumb|Mechanism]] | |||
The mechanism of GIP begins with the ingestion of food. | |||
== Disease == | == Disease == | ||
<scene name='10/1038867/Tirzepatide/1'>Tirzepatide</scene> | One of the most promising treatments to GIP malfunction is <scene name='10/1038867/Tirzepatide/1'>Tirzepatide</scene>. | ||
== Relevance == | == Relevance == | ||
Revision as of 14:10, 4 April 2024
H. sapiens Glucose-dependent Insulinotropic Polypeptide
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References
- ↑ Seino Y, Fukushima M, Yabe D. GIP and GLP-1, the two incretin hormones: Similarities and differences. J Diabetes Investig. 2010 Apr 22;1(1-2):8-23. PMID:24843404 doi:10.1111/j.2040-1124.2010.00022.x
- ↑ Mayendraraj A, Rosenkilde MM, Gasbjerg LS. GLP-1 and GIP receptor signaling in beta cells interactions and co-stimulation. Peptides. 2022 May;151:170749. PMID:35065096 doi:10.1016/j.peptides.2022.170749
