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| <StructureSection load='4diu' size='340' side='right' caption='Caption for this structure' scene=''> | | <StructureSection load='4diu' size='340' side='right' caption='Caption for this structure' scene=''> |
| <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | | <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. |
| == Overview of 'this type of enzyme' == | | == Overview of Esterase == |
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| The role in the body this would play based on results. Any potential implications of the enzyme if disrupted based on findings and related enzymes. | | The role in the body this would play based on results. Any potential implications of the enzyme if disrupted based on findings and related enzymes. |
Revision as of 16:44, 24 April 2024
Protein 4DIU: Structure, Function, and Significance in Biological Systems
Think of this like an abstract. Include a few sentences about the most important data you found about what type of enzyme this is.
| [1] or to the article describing Jmol [2] to the rescue.
Overview of Esterase
The role in the body this would play based on results. Any potential implications of the enzyme if disrupted based on findings and related enzymes.
Proposed Function
This protein has alpha/beta-hydrolase activity and is of the esterase family. The BLAST, InterPro, and Dali Search along with other bioinformatics analyses consistently matched with carboxylesterases and other esterase-like proteins. SwissDock and Chimera allowed for protein-ligand docking studies. Many of the highlighted interactions were ester-containing ligands and others were susceptible to hydrolysis. The isolated protein was introduced to 10 mM p-nitrophenyl acetate in a buffer with a pH of 6. Enzyme activity was measured, and the data was consistent with other hydrolases.
Structural highlights
Highlight the data that helped you come to your conclusion here including any relevant figures. Make sure to include potential substrates and binding sites.
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:https://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
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References
proteopedia link