Sandbox Ben Whiteside: Difference between revisions
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In order to restore basal amylin levels in mice, researchers have performed PEGylation, the addition of poly ethylene glycol, to amylin within residues 1-11 of the peptide, most likely at the two amine groups of K1<ref name="Guerreiro">PMID: 23818080</ref>. Administration of the modified amylin in mice showed evidence of reduced glycemia and prolonged action compared to endogenous amylin <ref name="Guerreiro" />. | In order to restore basal amylin levels in mice, researchers have performed PEGylation, the addition of poly ethylene glycol, to amylin within residues 1-11 of the peptide, most likely at the two amine groups of K1<ref name="Guerreiro">PMID: 23818080</ref>. Administration of the modified amylin in mice showed evidence of reduced glycemia and prolonged action compared to endogenous amylin <ref name="Guerreiro" />. | ||
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== References == | == References == | ||
<references/> | <references/> | ||
== Student Contributors == | == Student Contributors == | ||
Andrew Helmerich, Mathias Vander Eide, Ben Whiteside | Andrew Helmerich, Mathias Vander Eide, Ben Whiteside | ||
