Sandbox324: Difference between revisions
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Highlight the data that helped you come to your conclusion here including any relevant figures. Make sure to include potential substrates and binding sites. | Highlight the data that helped you come to your conclusion here including any relevant figures. Make sure to include potential substrates and binding sites. | ||
One of the distinctive structural characteristics of this protein is the alpha/beta-hydrolase (ABH) fold. Evidence for this fold consists of its structure (an open β-sheet surrounded by α-helices) and the presence of what is known as the "catalytic triad" (consisting of a nucleophile, an acid, and histidine)<ref>Holmquist, M. Alpha Beta-Hydrolase Fold Enzymes Structures, Functions and Mechanisms. Current Protein and Peptide Science 2000, 1 (2), 209–235. https://doi.org/10.2174/1389203003381405.</ref>. The presence of the active site residues His A 222, Asp A 192, and Ser A 93, as determined by SPRITE, Chimera, etc., confirms the presence of this catalytic triad. | |||
[Write about potential substrates] | [Write about potential substrates] | ||
