1uor: Difference between revisions

Line 1:

[[Image:1uor.gif|left|200px]]<br />

[[Image:1uor.gif|left|200px]]<br /><applet load="1uor" size="350" color="white" frame="true" align="right" spinBox="true"

<applet load="1uor" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

caption="1uor, resolution 2.80Å" />

'''X-RAY STUDY OF RECOMBINANT HUMAN SERUM ALBUMIN. PHASES DETERMINED BY MOLECULAR REPLACEMENT METHOD, USING LOW RESOLUTION STRUCTURE MODEL OF TETRAGONAL FORM OF HUMAN SERUM ALBUMIN'''<br />

==Overview==

The three-dimensional structure of human serum albumin has been determined, crystallographically to a resolution of 2.8 A. It comprises three, homologous domains that assemble to form a heart-shaped molecule. Each, domain is a product of two subdomains that possess common structural, motifs. The principal regions of ligand binding to human serum albumin are, located in hydrophobic cavities in subdomains IIA and IIIA, which exhibit, similar chemistry. The structure explains numerous physical phenomena and, should provide insight into future pharmacokinetic and genetically, engineered therapeutic applications of serum albumin.

The three-dimensional structure of human serum albumin has been determined crystallographically to a resolution of 2.8 A. It comprises three homologous domains that assemble to form a heart-shaped molecule. Each domain is a product of two subdomains that possess common structural motifs. The principal regions of ligand binding to human serum albumin are located in hydrophobic cavities in subdomains IIA and IIIA, which exhibit similar chemistry. The structure explains numerous physical phenomena and should provide insight into future pharmacokinetic and genetically engineered therapeutic applications of serum albumin.

==Disease==

Line 11:

Line 10:

==About this Structure==

1UOR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1UOR OCA].

1UOR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOR OCA].

==Reference==

Line 17:

Line 16:

[[Category: Homo sapiens]]

[[Category: Single protein]]

[[Category: Carter, D.C.]]

[[Category: Carter, D C.]]

[[Category: Ho, J.X.]]

[[Category: Ho, J X.]]

[[Category: metal-binding protein]]

[[Category: plasma protein]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Mon Nov 12 19~~:37:~~10 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:26:48 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:1uor.gif|left|200px]]<br />
+[[Image:1uor.gif|left|200px]]<br /><applet load="1uor" size="350" color="white" frame="true" align="right" spinBox="true"
-<applet load="1uor" size="450" color="white" frame="true" align="right" spinBox="true"
 caption="1uor, resolution 2.80&Aring;" />
 '''X-RAY STUDY OF RECOMBINANT HUMAN SERUM ALBUMIN. PHASES DETERMINED BY MOLECULAR REPLACEMENT METHOD, USING LOW RESOLUTION STRUCTURE MODEL OF TETRAGONAL FORM OF HUMAN SERUM ALBUMIN'''<br />
 ==Overview==
-The three-dimensional structure of human serum albumin has been determined, crystallographically to a resolution of 2.8 A. It comprises three, homologous domains that assemble to form a heart-shaped molecule. Each, domain is a product of two subdomains that possess common structural, motifs. The principal regions of ligand binding to human serum albumin are, located in hydrophobic cavities in subdomains IIA and IIIA, which exhibit, similar chemistry. The structure explains numerous physical phenomena and, should provide insight into future pharmacokinetic and genetically, engineered therapeutic applications of serum albumin.
+The three-dimensional structure of human serum albumin has been determined crystallographically to a resolution of 2.8 A. It comprises three homologous domains that assemble to form a heart-shaped molecule. Each domain is a product of two subdomains that possess common structural motifs. The principal regions of ligand binding to human serum albumin are located in hydrophobic cavities in subdomains IIA and IIIA, which exhibit similar chemistry. The structure explains numerous physical phenomena and should provide insight into future pharmacokinetic and genetically engineered therapeutic applications of serum albumin.
 ==Disease==
@@ Line 11: / Line 10: @@
 ==About this Structure==
-UOR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1UOR OCA].
+UOR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOR OCA].
 ==Reference==
@@ Line 17: / Line 16: @@
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
-[[Category: Carter, D.C.]]
+[[Category: Carter, D C.]]
-[[Category: Ho, J.X.]]
+[[Category: Ho, J X.]]
 [[Category: metal-binding protein]]
 [[Category: plasma protein]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 19:37:10 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:26:48 2008''