8k7r: Difference between revisions
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==Human Fc epsilon RI in complex with hIgE Fc (TMD disordered)== | |||
<StructureSection load='8k7r' size='340' side='right'caption='[[8k7r]], [[Resolution|resolution]] 3.56Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8k7r]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K7R FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.56Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k7r OCA], [https://pdbe.org/8k7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k7r RCSB], [https://www.ebi.ac.uk/pdbsum/8k7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k7r ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FCERA_HUMAN FCERA_HUMAN] Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ohto U]] | |||
[[Category: Shimizu T]] | |||
[[Category: Yui M]] | |||
[[Category: Zhang Z]] | |||
Latest revision as of 06:13, 4 December 2024
Human Fc epsilon RI in complex with hIgE Fc (TMD disordered)
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