8zhr: Difference between revisions
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==Cryo-EM structure of the full-length pAg-bound BTN2A1-BTN3A1-BTN3A2 complex== | |||
<StructureSection load='8zhr' size='340' side='right'caption='[[8zhr]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8zhr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZHR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZHR FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H6P:(2E)-4-HYDROXY-3-METHYLBUT-2-EN-1-YL+TRIHYDROGEN+DIPHOSPHATE'>H6P</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zhr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zhr OCA], [https://pdbe.org/8zhr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zhr RCSB], [https://www.ebi.ac.uk/pdbsum/8zhr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zhr ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BT3A2_HUMAN BT3A2_HUMAN] Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.<ref>PMID:21918970</ref> <ref>PMID:22767497</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Huang B]] | |||
[[Category: Su Q]] | |||
[[Category: Xin W]] | |||
[[Category: Zhou Q]] | |||
Latest revision as of 06:15, 26 November 2025
Cryo-EM structure of the full-length pAg-bound BTN2A1-BTN3A1-BTN3A2 complex
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