1s9b: Difference between revisions

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{{Seed}}
[[Image:1s9b.gif|left|200px]]
[[Image:1s9b.gif|left|200px]]


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{{STRUCTURE_1s9b|  PDB=1s9b  |  SCENE=  }}  
{{STRUCTURE_1s9b|  PDB=1s9b  |  SCENE=  }}  


'''Crystal Structure Analysis of the B-DNA GAATTCG'''
===Crystal Structure Analysis of the B-DNA GAATTCG===




==Overview==
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DNA oligonucleotides can be used in order to assemble highly structured materials. Oligonucleotides with sticky ends can form long linear structures, whereas branching is required to form two- and three-dimensional nanostructures. In this paper, we show that when Ni(2+) is attached to the N7 atom of guanine, it can also act as a branching point. Thus, we have found that the heptanucleotide d(GAATTCG) can assemble into long linear duplex structures, which cross in space to generate a cubic structure. The three-dimensional arrays are stabilized by phosphate-Ni(2+)-guanine interactions. For the first time, the crystallization of a B form DNA oligonucleotide in a cubic system is reported, space group I23. Large solvent cavities are found among the DNA duplexes.
The line below this paragraph, {{ABSTRACT_PUBMED_15212528}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 15212528 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15212528}}


==About this Structure==
==About this Structure==
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[[Category: Double helix]]
[[Category: Double helix]]
[[Category: Nickel]]
[[Category: Nickel]]
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