7h6h: Difference between revisions

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'''Unreleased structure'''


The entry 7h6h is ON HOLD
==THE 1.94 A CRYSTAL STRUCTURE OF HUMAN CATHEPSIN G IN COMPLEX WITH 1-[(7-fluoronaphthalen-1-yl)methyl]-3-[[methoxycarbonyl(methyl)amino]methyl]indole-2-carboxylic acid==
 
<StructureSection load='7h6h' size='340' side='right'caption='[[7h6h]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
Authors: Banner, D.W., Benz, J.M., Schlatter, D., Hilpert, H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7h6h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7H6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7H6H FirstGlance]. <br>
Description: THE 1.94 A CRYSTAL STRUCTURE OF HUMAN CATHEPSIN G IN COMPLEX WITH 1-[(7-fluoronaphthalen-1-yl)methyl]-3-[[methoxycarbonyl(methyl)amino]methyl]indole-2-carboxylic acid
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AO6:1-[(7-fluoranylnaphthalen-1-yl)methyl]-3-[[methoxycarbonyl(methyl)amino]methyl]indole-2-carboxylic+acid'>A1AO6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Hilpert, H]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7h6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7h6h OCA], [https://pdbe.org/7h6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7h6h RCSB], [https://www.ebi.ac.uk/pdbsum/7h6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7h6h ProSAT]</span></td></tr>
[[Category: Schlatter, D]]
</table>
[[Category: Banner, D.W]]
== Function ==
[[Category: Benz, J.M]]
[https://www.uniprot.org/uniprot/CATG_HUMAN CATG_HUMAN] Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride.<ref>PMID:8194606</ref> <ref>PMID:1861080</ref> <ref>PMID:1937776</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Banner DW]]
[[Category: Benz JM]]
[[Category: Hilpert H]]
[[Category: Schlatter D]]
Retrieved from "https://proteopedia.org/7h6h"