1sfo: Difference between revisions

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[[Image:1sfo.gif|left|200px]]
{{Seed}}
[[Image:1sfo.png|left|200px]]


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{{STRUCTURE_1sfo|  PDB=1sfo  |  SCENE=  }}  
{{STRUCTURE_1sfo|  PDB=1sfo  |  SCENE=  }}  


'''RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX'''
===RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX===




==Overview==
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The structure of an RNA polymerase II-transcribing complex has been determined in the posttranslocation state, with a vacancy at the growing end of the RNA-DNA hybrid helix. At the opposite end of the hybrid helix, the RNA separates from the template DNA. This separation of nucleic acid strands is brought about by interaction with a set of proteins loops in a strand/loop network. Formation of the network must occur in the transition from abortive initiation to promoter escape.
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{{ABSTRACT_PUBMED_14963331}}


==About this Structure==
==About this Structure==
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[[Category: Multiprotein complex]]
[[Category: Multiprotein complex]]
[[Category: Transcription]]
[[Category: Transcription]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 08:38:36 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:36:24 2008''

Revision as of 13:36, 28 July 2008

File:1sfo.png

Template:STRUCTURE 1sfo

RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX

Template:ABSTRACT PUBMED 14963331

About this Structure

1SFO is a Protein complex structure of sequences from Saccharomyces cerevisiae. This structure supersedes the now removed PDB entry 1r9r. Full crystallographic information is available from OCA.

Reference

Structural basis of transcription: separation of RNA from DNA by RNA polymerase II., Westover KD, Bushnell DA, Kornberg RD, Science. 2004 Feb 13;303(5660):1014-6. PMID:14963331

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