1sg7: Difference between revisions

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[[Image:1sg7.gif|left|200px]]
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[[Image:1sg7.png|left|200px]]


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{{STRUCTURE_1sg7|  PDB=1sg7  |  SCENE=  }}  
{{STRUCTURE_1sg7|  PDB=1sg7  |  SCENE=  }}  


'''NMR solution structure of the putative cation transport regulator ChaB'''
===NMR solution structure of the putative cation transport regulator ChaB===




==Overview==
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BACKGROUND: ChaB is a putative regulator of ChaA, a Na+/H+ antiporter that also has Ca+/H+ activity in E. coli. ChaB contains a conserved 60-residue region of unknown function found in other bacteria, archaeabacteria and a series of baculoviral proteins. As part of a structural genomics project, the structure of ChaB was elucidated by NMR spectroscopy. RESULTS: The structure of ChaB is composed of 3 alpha-helices and a small sheet that pack tightly to form a fold that is found in the cyclin-box family of proteins. CONCLUSION: ChaB is distinguished from its putative DNA binding sequence homologues by a highly charged flexible loop region that has weak affinity to Mg2+ and Ca2+ divalent metal ions.
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{{ABSTRACT_PUBMED_15306028}}


==About this Structure==
==About this Structure==
1SG7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG7 OCA].  
1SG7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG7 OCA].  


==Reference==
==Reference==
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[[Category: Montreal-kingston bacterial structural genomics initiative]]
[[Category: Montreal-kingston bacterial structural genomics initiative]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:31:25 2008''

Revision as of 08:31, 28 July 2008

File:1sg7.png

Template:STRUCTURE 1sg7

NMR solution structure of the putative cation transport regulator ChaB

Template:ABSTRACT PUBMED 15306028

About this Structure

1SG7 is a Single protein structure of sequence from Escherichia coli. Full experimental information is available from OCA.

Reference

The solution structure of ChaB, a putative membrane ion antiporter regulator from Escherichia coli., Osborne MJ, Siddiqui N, Iannuzzi P, Gehring K, BMC Struct Biol. 2004 Aug 11;4:9. PMID:15306028

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