9f6e: Difference between revisions

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'''Unreleased structure'''


The entry 9f6e is ON HOLD  until Paper Publication
==Human DNA polymerase epsilon bound to DNA and PCNA (ajar conformation)==
 
<StructureSection load='9f6e' size='340' side='right'caption='[[9f6e]], [[Resolution|resolution]] 3.74&Aring;' scene=''>
Authors: Roske, J.J., Yeeles, J.T.P.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9f6e]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9F6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9F6E FirstGlance]. <br>
Description: Human DNA polymerase epsilon bound to DNA and PCNA (ajar conformation)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.74&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2DA:2,3-DIDEOXYADENOSINE-5-MONOPHOSPHATE'>2DA</scene>, <scene name='pdbligand=DDS:2,3-DIDEOXYADENOSINE+TRIPHOSPHATE'>DDS</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
[[Category: Roske, J.J]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9f6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9f6e OCA], [https://pdbe.org/9f6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9f6e RCSB], [https://www.ebi.ac.uk/pdbsum/9f6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9f6e ProSAT]</span></td></tr>
[[Category: Yeeles, J.T.P]]
</table>
== Disease ==
[https://www.uniprot.org/uniprot/DPOE1_HUMAN DPOE1_HUMAN] Facial dysmorphism - immunodeficiency - livedo - short stature. Disease susceptibility is associated with variations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/DPOE1_HUMAN DPOE1_HUMAN] Participates in DNA repair and in chromosomal DNA replication.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Roske JJ]]
[[Category: Yeeles JTP]]

Latest revision as of 05:46, 7 August 2024

Human DNA polymerase epsilon bound to DNA and PCNA (ajar conformation)

9f6e, resolution 3.74Å

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