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| **[[1wuq]], [[1wur]] – TtGCH I + Zn + 8-oxo-GTP <br /> | | **[[1wuq]], [[1wur]] – TtGCH I + Zn + 8-oxo-GTP <br /> |
| **[[5k95]] – NgGCH 1B + Zn + 8-oxo-GTP <br /> | | **[[5k95]] – NgGCH 1B + Zn + 8-oxo-GTP <br /> |
| | **[[8g6c]], [[8g8v]] – BpGCH 1B + cation – ''Burkholderia pseudomallei''<br /> |
| | **[[8tcc]] – BpGCH 1B + dehydrocostus lactone<br /> |
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| *GTP cyclohydrolase II or UTP cyclohydrolase | | *GTP cyclohydrolase II or UTP cyclohydrolase |
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| **[[1a4i]], [[6ecr]] – hMCH + NADP <br /> | | **[[1a4i]], [[6ecr]] – hMCH + NADP <br /> |
| **[[1dig]], [[1dia]], [[1dib]],[[6ecp]], [[6ecq]], [[5tc4]], [[7ehj]] – hMCH + NADP + inhibitor<br /> | | **[[1dig]], [[1dia]], [[1dib]], [[5tc4]], [[6ecp]], [[6ecq]], [[6s4a]], [[7ehj]], [[7qei]], [[9is9]], [[9isc]], [[9it3]], [[9it6]], [[9ita]] – hMCH + NADP + inhibitor<br /> |
| **[[6jib]], [[6jid]], [[6kg2]], [[7ehm]], [[7ehn]], [[7ehv]] – hMCH + inhibitor<br /> | | **[[6jib]], [[6jid]], [[6kg2]], [[7ehm]], [[7ehn]], [[7ehv]] – hMCH + inhibitor<br /> |
| **[[2c2x]], [[2c2y]] – MCH – ''Mycobacterium tuberculosis''<br /> | | **[[2c2x]], [[2c2y]] – MCH – ''Mycobacterium tuberculosis''<br /> |
| **[[7vg4]] – MeMCH – ''Methylorubrum extoquens''<br /> | | **[[7vg4]] – MeMCH – ''Methylorubrum extoquens''<br /> |
| **[[7vg5]] – MeMCH + THF<br /> | | **[[7vg5]] – MeMCH + THF<br /> |
| | **[[8wfc]] – MCH – ''Porphyromonas gingivalis''<br /> |
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| *Phosphoribosyl-AMP cyclohydrolase | | *Phosphoribosyl-AMP cyclohydrolase |
3D structures of cyclohydrolase
Updated on 17-February-2025
{"openlevels":0}
- GTP cyclohydrolase I
- 1fb1, 6z87 – hGCH I + Zn – human
- 1gtp – EcGCH I – Escherichia coli
- 5k9g – NgGCH IB + Zn – Neisseria gonorrhoeae
- 3d2o – NgGCH IB + Mn
- 1wm9 – TtGCH I + Zn – Thermus thermophilus
- 4uqf – GCH I – Listeria monocytogenes
- GTP cyclohydrolase I complexes
- 6z80 – hGCH I + GFRP + Zn + 8-oxo-GTP – Cryo EM
- 6z85 – hGCH I + GFRP + Zn + dihydrobiopterin – Cryo EM
- 6z86 – hGCH I + Zn + deaza-GTP
- 6z88, 6z89 – hGCH I + Zn + inhibitor
- 7alc – hGCH I + Zn + GFRP
- 7alb, 7alq – hGCH I + Zn + deaza-GTP + GFRP
- 7ala – hGCH I + Zn + inhibitor + GFRP
- 1is7 – rGCH I + GFRP - rat
- 1is8 – rGCH I + GFRP + Zn
- 1wpl – rGCH I + GFRP + Zn + dihydrobiopterin
- 1a8r, 1a9c, 1n3r, 1n3t, 1n3s – EcGCH I (mutant) + GTP
- 4du6 – GCH I + GTP – Yersinia pseudotuberculosis
- 1fbx – EcGCH I + Zn
- 1wuq, 1wur – TtGCH I + Zn + 8-oxo-GTP
- 5k95 – NgGCH 1B + Zn + 8-oxo-GTP
- 8g6c, 8g8v – BpGCH 1B + cation – Burkholderia pseudomallei
- 8tcc – BpGCH 1B + dehydrocostus lactone
- GTP cyclohydrolase II or UTP cyclohydrolase
- 2bz1 – EcGCH II + Zn
- 2bz0 – EcGCH II + Zn + phosphomethylphosphonic acid guanylate
- 4rl4 – GCH II – Helicobacter pylori
- 7ej3 – RwGCH II – Rhodococcus wratislaviensis
- 7eev – RwGCH II + UTP
- GTP cyclohydrolase III
- 2qv6 – GCH III + GTP + Ca – Methanocaldococcus jannaschii
- IMP cyclohydrolase
- 2ntm – MtICH – Methanothermobacter thermoautotrophicus
- 2ntk – MtICH + IMP
- 2ntl – MtICH + AICAR
- Methenyltetrahydromethanopterin cyclohydrolase
- 1qlm – MCH – Methanopyrus kandleri
- 4fio – MCH – Methanobrevibacter ruminatium
- 4gvr – AfMCH – Archaeoglobus fulgidus
- 4gvq – AfMCH + tetrahydromethanopterin
- 4gvs – AfMCH + N5-formyl-tetrahydromethanopterin
- Methylenetetrahydrofolate dehydrogenase/cyclohydrolase
- 1a4i, 6ecr – hMCH + NADP
- 1dig, 1dia, 1dib, 5tc4, 6ecp, 6ecq, 6s4a, 7ehj, 7qei, 9is9, 9isc, 9it3, 9it6, 9ita – hMCH + NADP + inhibitor
- 6jib, 6jid, 6kg2, 7ehm, 7ehn, 7ehv – hMCH + inhibitor
- 2c2x, 2c2y – MCH – Mycobacterium tuberculosis
- 7vg4 – MeMCH – Methylorubrum extoquens
- 7vg5 – MeMCH + THF
- 8wfc – MCH – Porphyromonas gingivalis
- Phosphoribosyl-AMP cyclohydrolase
- 1zps – MtPCH + Cd
- 7bgm – MetPCH + Zn – Medicago truncatula
- 7bgn – MetPCH + Zn + AMP
