9fgq: Difference between revisions
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==Structure of human APC3loop 375-381 bound to the NCP== | |||
<StructureSection load='9fgq' size='340' side='right'caption='[[9fgq]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9fgq]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FGQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9fgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fgq OCA], [https://pdbe.org/9fgq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fgq RCSB], [https://www.ebi.ac.uk/pdbsum/9fgq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fgq ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Muhammad | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/CDC27_HUMAN CDC27_HUMAN] Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<ref>PMID:18485873</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Alfieri C]] | |||
[[Category: Muhammad R]] | |||
[[Category: Young RVC]] | |||
Latest revision as of 06:38, 24 July 2024
Structure of human APC3loop 375-381 bound to the NCP
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