1ssk: Difference between revisions

Line 1:

[[Image:1ssk.~~gif~~|left|200px]]

[[Image:1ssk.png|left|200px]]

<!--

Line 9:

Line 10:

~~'''~~Structure of the N-terminal RNA-binding Domain of the SARS CoV Nucleocapsid Protein~~'''~~

===Structure of the N-terminal RNA-binding Domain of the SARS CoV Nucleocapsid Protein===

~~==Overview==~~

<!--

The ~~severe acute respiratory syndrome (SARS) virus belongs~~ to the ~~Coronaviridea family of viruses~~. ~~Its virion encodes several proteins including a replicase and four structural proteins~~. ~~Here we describe the three-dimensional structure of the N-terminal domain of the SARS coronavirus (CoV~~) nucleocapsid protein. The protein consists of a five-stranded beta sheet with a folding topology distinct from other RNA-binding proteins. Single-stranded RNAs bind to the protein surface at the junction between a flexible, ~~positively charged beta hairpin and~~ the ~~core structure~~. ~~NMR~~-~~based screening was used to identify low molecular weight compounds that bind to this site.~~

The line below this paragraph, {{ABSTRACT_PUBMED_15147189}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 15147189 is the PubMed ID number.

-->

==About this Structure==

1SSK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_sars_coronavirus Human sars coronavirus]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SSK OCA].

1SSK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_sars_coronavirus Human sars coronavirus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SSK OCA].

==Reference==

Line 33:

Line 37:

[[Category: Yu, L.]]

[[Category: Nucleocapsid protein]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 09~~:05:33 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:22:20 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:1ssk.gif|left|200px]]
+{{Seed}}
+[[Image:1ssk.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_1ssk|  PDB=1ssk  |  SCENE=  }}
-'''Structure of the N-terminal RNA-binding Domain of the SARS CoV Nucleocapsid Protein'''
+===Structure of the N-terminal RNA-binding Domain of the SARS CoV Nucleocapsid Protein===
-==Overview==
+<!--
-The severe acute respiratory syndrome (SARS) virus belongs to the Coronaviridea family of viruses. Its virion encodes several proteins including a replicase and four structural proteins. Here we describe the three-dimensional structure of the N-terminal domain of the SARS coronavirus (CoV) nucleocapsid protein. The protein consists of a five-stranded beta sheet with a folding topology distinct from other RNA-binding proteins. Single-stranded RNAs bind to the protein surface at the junction between a flexible, positively charged beta hairpin and the core structure. NMR-based screening was used to identify low molecular weight compounds that bind to this site.
+The line below this paragraph, {{ABSTRACT_PUBMED_15147189}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 15147189 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_15147189}}
 ==About this Structure==
-SSK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_sars_coronavirus Human sars coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SSK OCA].
+SSK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_sars_coronavirus Human sars coronavirus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SSK OCA].
 ==Reference==
@@ Line 33: / Line 37: @@
 [[Category: Yu, L.]]
 [[Category: Nucleocapsid protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 09:05:33 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:22:20 2008''