1svb: Difference between revisions

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[[Image:1svb.gif|left|200px]]
{{Seed}}
[[Image:1svb.png|left|200px]]


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{{STRUCTURE_1svb|  PDB=1svb  |  SCENE=  }}  
{{STRUCTURE_1svb|  PDB=1svb  |  SCENE=  }}  


'''ENVELOPE GLYCOPROTEIN FROM TICK-BORNE ENCEPHALITIS VIRUS'''
===ENVELOPE GLYCOPROTEIN FROM TICK-BORNE ENCEPHALITIS VIRUS===




==Overview==
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The crystallographically determined structure of a soluble fragment from the major envelope protein of a flavivirus reveals an unusual architecture. The flat, elongated dimer extends in a direction that would be parallel to the viral membrane. Residues that influence binding of monoclonal antibodies lie on the outward-facing surface of the protein. The clustering of mutations that affect virulence in various flaviviruses indicates a possible receptor binding site and, together with other mutational and biochemical data, suggests a picture for the fusion-activating, conformational change triggered by low pH.
The line below this paragraph, {{ABSTRACT_PUBMED_7753193}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 7753193 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7753193}}


==About this Structure==
==About this Structure==
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[[Category: Rey, F A.]]
[[Category: Rey, F A.]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 09:10:34 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:10:19 2008''
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