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'''Unreleased structure'''


The entry 9ims is ON HOLD  until Paper Publication
==Crystal structure of C45 isoprenyl diphosphate synthase Rv0562 variant D98R/D223R from Mycobacterium tuberculosis==
 
<StructureSection load='9ims' size='340' side='right'caption='[[9ims]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9ims]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IMS FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ims FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ims OCA], [https://pdbe.org/9ims PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ims RCSB], [https://www.ebi.ac.uk/pdbsum/9ims PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ims ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NPPPS_MYCTU NPPPS_MYCTU] Catalyzes the sequential condensations of isopentenyl pyrophosphate (IPP) with geranyl diphosphate (GPP) to yield (2E,6E)-farnesyl diphosphate (E,E-FPP), with E,E-FPP to yield geranylgeranyl diphosphate (GGPP) and with GGPP to yield nonaprenyl diphosphate (PubMed:23091471, PubMed:30301210, PubMed:32495977). May also have weak activity with dimethylallyl diphosphate (DMAPP) (PubMed:23091471).<ref>PMID:23091471</ref> <ref>PMID:30301210</ref> <ref>PMID:32495977</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Chen C-C]]
[[Category: Guo R-T]]
[[Category: Wang Q]]
[[Category: Yang Y]]
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