9imu: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The ~~entry~~ 9imu is ~~ON HOLD until Paper Publication~~

==The complex of rice immune receptor RGA5-HMA8 with rice blast effector protein AVR-PikD==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9imu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa] and [https://en.wikipedia.org/wiki/Pyricularia_oryzae Pyricularia oryzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IMU FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9imu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9imu OCA], [https://pdbe.org/9imu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9imu RCSB], [https://www.ebi.ac.uk/pdbsum/9imu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9imu ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/RGA5R_ORYSJ RGA5R_ORYSJ] Disease resistance (R) protein that recognizes the AVR-Pia and AVR1-CO39 effector avirulence proteins from M.oryzae. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Contribution of RGA4 is required to recognize the effector avirulence proteins AVR-Pia and AVR1-CO39 from M.oryzae (PubMed:21251109, PubMed:23548743). Acts as a repressor of the RGA4-mediated cell death activation. Upon infection, recognition and binding of the AVR effectors relieve the RGA5-mediated repression and triggers the hypersensitive response (PubMed:25024433). Immune response triggered by the RGA4-RGA5 -mediated recognition of AVR1-CO39 confers resistance to X.oryzae pathovars (PubMed:27289079).<ref>PMID:21251109</ref> <ref>PMID:23548743</ref> <ref>PMID:25024433</ref> <ref>PMID:27289079</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Oryza sativa]]

[[Category: Pyricularia oryzae]]

[[Category: Liu J]]

[[Category: Zhang X]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9imu is ON HOLD  until Paper Publication
+==The complex of rice immune receptor RGA5-HMA8 with rice blast effector protein AVR-PikD==
+<StructureSection load='9imu' size='340' side='right'caption='[[9imu]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9imu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa] and [https://en.wikipedia.org/wiki/Pyricularia_oryzae Pyricularia oryzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IMU FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9imu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9imu OCA], [https://pdbe.org/9imu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9imu RCSB], [https://www.ebi.ac.uk/pdbsum/9imu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9imu ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RGA5R_ORYSJ RGA5R_ORYSJ] Disease resistance (R) protein that recognizes the AVR-Pia and AVR1-CO39 effector avirulence proteins from M.oryzae. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Contribution of RGA4 is required to recognize the effector avirulence proteins AVR-Pia and AVR1-CO39 from M.oryzae (PubMed:21251109, PubMed:23548743). Acts as a repressor of the RGA4-mediated cell death activation. Upon infection, recognition and binding of the AVR effectors relieve the RGA5-mediated repression and triggers the hypersensitive response (PubMed:25024433). Immune response triggered by the RGA4-RGA5 -mediated recognition of AVR1-CO39 confers resistance to X.oryzae pathovars (PubMed:27289079).<ref>PMID:21251109</ref> <ref>PMID:23548743</ref> <ref>PMID:25024433</ref> <ref>PMID:27289079</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Oryza sativa]]
+[[Category: Pyricularia oryzae]]
+[[Category: Liu J]]
+[[Category: Zhang X]]