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==CryoEM Structure of a FtsH Helical Assembly in the Presence of ATP== | |||
<StructureSection load='8vw9' size='340' side='right'caption='[[8vw9]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8vw9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8VW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8VW9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.6Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8vw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8vw9 OCA], [https://pdbe.org/8vw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8vw9 RCSB], [https://www.ebi.ac.uk/pdbsum/8vw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8vw9 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FTSH_THEMA FTSH_THEMA] Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.[HAMAP-Rule:MF_01458] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Thermotoga maritima]] | |||
[[Category: Egelman EH]] | |||
[[Category: Li Y]] | |||
[[Category: Tezcan FA]] | |||
[[Category: Wang F]] | |||
[[Category: Zhang Z]] | |||
[[Category: Zhu J]] | |||
Latest revision as of 06:11, 15 January 2025
CryoEM Structure of a FtsH Helical Assembly in the Presence of ATP
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