9gm4: Difference between revisions
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==Crystal structure of elastase LasB from Pseudomonas aeruginosa PA14 in complex with 6558== | |||
<StructureSection load='9gm4' size='340' side='right'caption='[[9gm4]], [[Resolution|resolution]] 1.51Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9gm4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PA14 Pseudomonas aeruginosa PA14]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GM4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GM4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1IM0:(2~{R})-2-(2-methylpropyl)-~{N}-oxidanyl-~{N}-[(3~{R})-2-oxidanylidene-1-phenyl-pyrrolidin-3-yl]propanediamide'>A1IM0</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gm4 OCA], [https://pdbe.org/9gm4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gm4 RCSB], [https://www.ebi.ac.uk/pdbsum/9gm4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gm4 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ELAS_PSEAB ELAS_PSEAB] Cleaves host elastase, collagen, IgI and several complement components as well as endogenous pro-aminopeptidase, pro-chitin-binding protein (cbpD). Cleaves its own pro-peptide. Involved in the pathogenesis of P.aeruginosa infections.[UniProtKB:P14756] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pseudomonas aeruginosa PA14]] | |||
[[Category: Koehnke J]] | |||
[[Category: Kolling D]] | |||
Latest revision as of 04:06, 14 September 2025
Crystal structure of elastase LasB from Pseudomonas aeruginosa PA14 in complex with 6558
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